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Name of the Condition and Other Names It’s Known By • Gallstones • Cholelithiasis What are Gallstones? Gallstones are hardened pieces of digestive fluid that form in the gallbladder. The gallbladder is a small organ under the liver that stores bile, a fluid made in the liver to help digestion. Gallstones can range in size from a grain of sand to a golf ball and can be made of cholesterol, bilirubin, or a combination of both. They can cause symptoms when they block the flow of bile from the gallb